TRAPPC12

Across TCGA patient cohorts, TRAPPC12 mutation is significantly associated with the RNA expression of many other genes, with 2,711 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRAPPC12-associated genes across cancer lineages are OR10B1P, SLC25A5P4, and OSTCP6. Each is linked with TRAPPC12 in more than 2 cancer types. Because this analysis shows association rather than direction, both TRAPPC12-to-partner and partner-to-TRAPPC12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10B1P grouped by TRAPPC12-low versus TRAPPC12-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAPPC12→partner) and Y-score (partner→TRAPPC12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	OR10B1P →	+1.169	+4.112	<.001	.004	3	3
SKCM	SLC25A5P4 →	+0.045	+3.661	.004	.009	3	3
UCEC	OSTCP6 →	+0.269	+2.344	.004	.001	3	3
UCEC	TUBAP1 →	+0.065	+2.381	.008	<.001	3	3
COAD	H2BC13 →	+1.302	+3.210	<.001	.009	3	2
COAD	LINC01022 →	+0.380	+3.099	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,711 associations by consensus.

OR10B1P by TRAPPC12 expression — BLCA

Explore this box plot interactively →