TRAPPC12

Across TCGA cell cohorts, TRAPPC12 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,415 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible TRAPPC12-associated GO terms across cancer lineages are Regulation of kinetochore assembly, Positive regulation of intracellular steroid hormone receptor signaling pathway, and mRNA destabilization. Each is linked with TRAPPC12 in more than 14 cancer types. Because this analysis shows association rather than direction, both TRAPPC12-to-partner and partner-to-TRAPPC12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of kinetochore assembly grouped by TRAPPC12-low versus TRAPPC12-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAPPC12→partner) and Y-score (partner→TRAPPC12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Regulation of kinetochore assembly →	+0.100	+0.593	<.001	<.001	3	15
URINARY_TRACT	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.156	+0.490	.002	.007	2	12
BLOOD_Myeloma	mRNA destabilization →	+0.039	+0.578	.001	.004	3	11
UPPER_AERODIGESTIVE_TRACT	Protein localization to cytoplasmic stress granule →	+0.130	+0.880	.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Symbiont-mediated disruption of host cellular anatomical structure →	+0.115	+0.791	.002	.001	3	10
UPPER_AERODIGESTIVE_TRACT	Symbiont-mediated disruption of host anatomical structure →	+0.115	+0.791	.002	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,415 associations by consensus.

Regulation of kinetochore assembly by TRAPPC12 expression — URINARY_TRACT

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