TRAPPC11

Across TCGA pan-cancer cohorts, TRAPPC11 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated TRAPPC11 data layer compared with 26 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher TRAPPC11 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated TRAPPC11 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and HNSC show a favorable association.

COAD, CCRCC, and HNSC are the cancer types where TRAPPC11 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Tertile	All	0.905	1.000	.018	42	view →
CCRCC	DFS	Quartile	All	0.879	0.550	.002	38	view →
HNSC	DFS	Median	III,IV	0.886	0.303	.007	22	view →
OV	DFS	Median	All	0.942	0.547	.003	20	view →
PDAC	DFS	Median	All	0.567	0.870	.004	19	view →
LUAD	DFS	Median	III,IV	0.885	0.595	.017	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

TRAPPC11–COAD (DFS)

Open the COAD breakdown →