TRAPPC10

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, TRAPPC10 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated TRAPPC10 data layer compared with 27 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher TRAPPC10 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated TRAPPC10 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and PDAC show a favorable association.

LUAD, GBM, and CCRCC are the cancer types where TRAPPC10 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LUADOSMedianII,III,IV0.5110.804.02510view →
GBMDFSQuartileAll0.2100.510.0266view →
CCRCCDFSMedianII,III,IV1.0000.514.0226view →
PDACOSTertileAll0.9010.785.0263view →
LSCCOSTertileII,III,IV0.5020.862.0293view →
HNSCOSMedianIII,IV0.5470.782.0231view →
Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

TRAPPC10–LUAD (OS)

Kaplan–Meier survival curve for TRAPPC10 mass-spec protein-high vs -low samples in LUAD.

Open the LUAD breakdown →

Exploration