TRAPPC10

Across TCGA cell cohorts, TRAPPC10 mutation is significantly associated with the RNA expression of many other genes, with 412 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TRAPPC10-associated genes across cancer lineages are VWA3B, KRTAP17-1, and SSX7. Each is linked with TRAPPC10 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRAPPC10-to-partner and partner-to-TRAPPC10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, VWA3B grouped by TRAPPC10-low versus TRAPPC10-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAPPC10→partner) and Y-score (partner→TRAPPC10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	VWA3B →	+0.020	+4.285	.007	.003	3	1
SOFT_TISSUE	KRTAP17-1 →	+0.026	+5.369	<.001	.004	3	1
STOMACH	SSX7 →	+0.433	+5.285	<.001	.003	3	1
BLOOD_Leukemia	SLC7A14 →	+0.005	+4.060	<.001	.003	3	1
BLOOD_Leukemia	ANKRD30BL →	+1.062	+3.874	<.001	.005	3	1
BLOOD_Leukemia	KRT6C →	+0.021	+4.037	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 412 associations by consensus.

VWA3B by TRAPPC10 expression — BLOOD_Myeloma

Explore this box plot interactively →