TRAPPC1

Across TCGA pan-cancer cohorts, TRAPPC1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated TRAPPC1 data layer compared with 28 for mass-spec protein.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher TRAPPC1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated TRAPPC1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and LSCC show a favorable association.

PDAC, CCRCC, and HNSC are the cancer types where TRAPPC1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Tertile	All	0.654	0.837	.019	6	view →
CCRCC	DFS	Median	All	0.807	0.659	.021	3	view →
HNSC	DFS	Tertile	III,IV	0.662	0.866	.037	2	view →
LUAD	DFS	Quartile	II,III,IV	0.736	0.921	.045	1	view →
LSCC	OS	Median	II,III,IV	0.863	0.695	.044	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

TRAPPC1–PDAC (DFS)

Open the PDAC breakdown →