TRAPPC1

Across TCGA patient cohorts, TRAPPC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,165 significant associations in total. THYM shows the largest number of these associations.

The most reproducible TRAPPC1-associated GO terms across cancer lineages are [4Fe-4S] cluster assembly, Protein retention in Golgi apparatus, and Mitochondrial proton-transporting ATP synthase complex assembly. Each is linked with TRAPPC1 in more than 25 cancer types. Because this analysis shows association rather than direction, both TRAPPC1-to-partner and partner-to-TRAPPC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, [4Fe-4S] cluster assembly grouped by TRAPPC1-low versus TRAPPC1-high in DLBC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAPPC1→partner) and Y-score (partner→TRAPPC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	[4Fe-4S] cluster assembly →	+0.074	+0.495	<.001	.001	3	26
DLBC	Protein retention in Golgi apparatus →	-0.069	-0.460	<.001	<.001	3	26
MESO	Mitochondrial proton-transporting ATP synthase complex assembly →	+0.054	+0.573	<.001	<.001	3	26
THYM	Golgi ribbon formation →	-0.074	-0.741	<.001	<.001	3	25
ESCA	Regulation of alternative mRNA splicing, via spliceosome →	-0.049	-0.431	<.001	<.001	2	26
LAML	Synaptic vesicle endosomal processing →	-0.044	-0.477	<.001	<.001	3	24

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,165 associations by consensus.

[4Fe-4S] cluster assembly by TRAPPC1 expression — DLBC

Explore this box plot interactively →