TRAP1

Across TCGA pan-cancer cohorts, TRAP1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated TRAP1 data layer compared with 23 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher TRAP1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated TRAP1 expression acts as an unfavorable survival marker, although some lineages such as GBM show a favorable association.

CCRCC, LSCC, and LUAD are the cancer types where TRAP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	All	0.614	0.883	.002	19	view →
LSCC	DFS	Quartile	III,IV	0.578	0.918	.045	8	view →
LUAD	DFS	Quartile	All	0.466	1.000	.020	6	view →
GBM	OS	Median	All	0.638	0.397	.019	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

TRAP1–CCRCC (DFS)

Open the CCRCC breakdown →