TRAM2

Across TCGA patient cohorts, TRAM2 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,608 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible TRAM2-associated proteins across cancer lineages are MMP14, P3H3, and CRTAP. Each is linked with TRAM2 in more than 7 cancer types. Because this analysis shows association rather than direction, both TRAM2-to-partner and partner-to-TRAM2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRAM2 versus MMP14 in OV, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAM2→partner) and Y-score (partner→TRAM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MMP14 →	+0.585	+1.162	<.001	<.001	3	8
CCRCC	P3H3 →	+0.599	+0.593	.001	.003	3	8
PDAC	CRTAP →	+0.480	+0.376	<.001	<.001	3	8
UCEC	FKBP9 →	+0.507	+0.456	<.001	<.001	3	8
GBM	SERPINH1 →	+0.767	+0.743	<.001	<.001	3	7
OV	THBS3 →	+0.779	+1.084	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,608 associations by consensus.

TRAM2 vs MMP14 — OV

Explore this scatter interactively →