TRAM2

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, TRAM2 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TRAM2-associated genes across cancer lineages are CBLN4. Each is linked with TRAM2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRAM2-to-partner and partner-to-TRAM2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CBLN4 grouped by TRAM2-low versus TRAM2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAM2→partner) and Y-score (partner→TRAM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaCBLN4 →+0.006+5.539<.001.00331
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

CBLN4 by TRAM2 expression — BLOOD_Leukemia

Box plot of CBLN4 in TRAM2-low vs TRAM2-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration