TRAM1L1

Across TCGA cell cohorts, TRAM1L1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,034 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible TRAM1L1-associated GO terms across cancer lineages are Regulation of syncytium formation by plasma membrane fusion, Autophagosome assembly, and Endoplasmic reticulum to Golgi vesicle-mediated transport. Each is linked with TRAM1L1 in more than 10 cancer types. Because this analysis shows association rather than direction, both TRAM1L1-to-partner and partner-to-TRAM1L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of syncytium formation by plasma membrane fusion grouped by TRAM1L1-low versus TRAM1L1-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAM1L1→partner) and Y-score (partner→TRAM1L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of syncytium formation by plasma membrane fusion →	+0.085	+1.462	.001	<.001	3	11
STOMACH	Autophagosome assembly →	+0.078	+1.635	<.001	<.001	3	9
STOMACH	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.068	+0.982	<.001	.001	3	9
BONE	Vesicle budding from membrane →	+0.066	+1.402	<.001	<.001	3	8
STOMACH	Cytoplasmic translation →	+0.113	+1.452	<.001	.001	3	8
STOMACH	Autophagosome organization →	+0.080	+1.635	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,034 associations by consensus.

Regulation of syncytium formation by plasma membrane fusion by TRAM1L1 expression — OVARY

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