TRAM1

Across TCGA patient cohorts, TRAM1 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,768 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible TRAM1-associated proteins across cancer lineages are VCPIP1, ARFGEF1, and YTHDF3. Each is linked with TRAM1 in more than 5 cancer types. Because this analysis shows association rather than direction, both TRAM1-to-partner and partner-to-TRAM1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRAM1 versus VCPIP1 in BRCA, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAM1→partner) and Y-score (partner→TRAM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	VCPIP1 →	+0.237	+0.499	<.001	<.001	3	6
BRCA	ARFGEF1 →	+0.576	+0.516	<.001	<.001	3	6
OV	YTHDF3 →	+0.386	+1.000	<.001	<.001	3	6
OV	NCOA2 →	+0.304	+1.014	<.001	<.001	3	5
COAD	RAB2A →	+0.234	+0.454	.002	.001	3	4
CCRCC	LACTB2 →	+0.482	+0.685	.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,768 associations by consensus.

TRAM1 vs VCPIP1 — BRCA

Explore this scatter interactively →