TRAM1

Across TCGA cell cohorts, TRAM1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,379 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible TRAM1-associated GO terms across cancer lineages are Nuclear membrane reassembly, Endoplasmic reticulum to cytosol transport, and Retrograde protein transport, ER to cytosol. Each is linked with TRAM1 in more than 13 cancer types. Because this analysis shows association rather than direction, both TRAM1-to-partner and partner-to-TRAM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear membrane reassembly grouped by TRAM1-low versus TRAM1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAM1→partner) and Y-score (partner→TRAM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Nuclear membrane reassembly →	+0.087	+0.716	.003	.005	3	14
BLOOD_Lymphoma	Endoplasmic reticulum to cytosol transport →	+0.114	+0.874	.001	<.001	3	13
BLOOD_Lymphoma	Retrograde protein transport, ER to cytosol →	+0.114	+0.874	.001	<.001	3	13
BLOOD_Myeloma	ERAD pathway →	+0.108	+1.889	<.001	<.001	3	13
OESOPHAGUS	Positive regulation of protein exit from endoplasmic reticulum →	+0.171	+1.064	<.001	<.001	3	13
BONE	Cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	-0.152	-0.810	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,379 associations by consensus.

Nuclear membrane reassembly by TRAM1 expression — OESOPHAGUS

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