Across TCGA pan-cancer cohorts, TRAJ7 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of TRAJ7’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where TRAJ7 RNA is repressed in tumor relative to normal tissue. In most cancer types TRAJ7 is over-expressed in tumor, although a few such as LUSC and COAD show the opposite, repressed pattern.

LUSC, KIRC, and BRCA are the cancer types where TRAJ7 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TRAJ7 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	Female	All	−0.690	.015	4	view →
KIRC	All	II,III,IV	+0.235	.029	3	view →
BRCA	All	All	+0.230	.031	3	view →
COAD	Female	All	−0.426	.002	2	view →
LUAD	All	All	+0.370	.041	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: TRAJ7 RNA expression & survival · all TRAJ7 data types