Across TCGA patient cohorts, TRAJ61 protein abundance is significantly associated with the RNA expression of many other genes, with 2,492 significant associations in total. COAD shows the largest number of these associations.

The most reproducible TRAJ61-associated genes across cancer lineages are IGLV4-60, IGHV3-48, and IGHV3-53. Each is linked with TRAJ61 in more than 2 cancer types. Because this analysis shows association rather than direction, both TRAJ61-to-partner and partner-to-TRAJ61 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAJ61→partner) and Y-score (partner→TRAJ61) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	IGLV4-60 →	+3.023	+0.874	<.001	<.001	3	3
BRCA	IGHV3-48 →	+2.971	+1.155	<.001	<.001	3	3
BRCA	IGHV3-53 →	+2.635	+1.199	<.001	<.001	3	3
COAD	CD79B →	+1.064	+0.868	<.001	<.001	3	3
BRCA	IGHA2 →	+3.194	+1.068	<.001	<.001	3	3
LSCC	BIN2 →	+0.815	+0.980	.002	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,492 associations by consensus.

Exploration

TRAJ61 survival (RNA) · tumor vs normal (RNA) · all TRAJ61 data types