TRAJ60

Across TCGA pan-cancer cohorts, TRAJ60 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated TRAJ60 data layer.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher TRAJ60 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated TRAJ60 expression acts as an unfavorable survival marker, although some lineages such as LUAD and THYM show a favorable association.

READ, LUAD, and COAD are the cancer types where TRAJ60 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
READ	OS	Tertile	All	0.069	0.917	<.001	36	view →
LUAD	OS	Tertile	All	0.838	0.325	.006	33	view →
COAD	OS	Tertile	II,III,IV	0.245	0.570	.014	24	view →
LGG	OS	Tertile	All	0.101	0.909	<.001	18	view →
UCEC	OS	Tertile	All	0.774	0.928	.018	18	view →
KIRC	DFS	Tertile	III,IV	0.486	0.664	.039	9	view →
GBM	OS	Tertile	All	0.201	0.415	.047	9	view →
THCA	DFS	Tertile	All	0.085	0.811	<.001	9	view →
ESCA	OS	Tertile	III,IV	0.292	0.578	.048	9	view →
LIHC	OS	Tertile	All	0.441	0.785	.016	9	view →
THYM	OS	Tertile	All	1.000	0.825	.031	7	view →
LAML	DFS	Quartile	All	0.523	0.322	.045	4	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

TRAJ60–READ (OS)

Open the READ breakdown →