Across TCGA pan-cancer cohorts, TRAJ59 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of TRAJ59’s most consistent transcriptional readouts.
The strongest signal is observed in lung adenocarcinoma (LUAD), where TRAJ59 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TRAJ59 is over-expressed in tumor.
LUAD are the cancer types where TRAJ59 tumor–normal differential expression is most reproducible.