Across TCGA pan-cancer cohorts, TRAJ58 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of TRAJ58’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where TRAJ58 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TRAJ58 is over-expressed in tumor.

LUAD and KIRC are the cancer types where TRAJ58 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TRAJ58 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	All	All	+0.204	.028	1	view →
KIRC	All	All	+0.079	.047	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: TRAJ58 RNA expression & survival · all TRAJ58 data types