TRAJ54

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, TRAJ54 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated TRAJ54 data layer.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher TRAJ54 RNA is associated with better overall survival. In most high-consensus cancer types, elevated TRAJ54 expression acts as an unfavorable survival marker, although some lineages such as STAD and LUAD show a favorable association.

STAD, READ, and KIRP are the cancer types where TRAJ54 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
STADOSTertileIII,IV0.6530.238.00969view →
READDFSTertileIII,IV0.2850.771<.00154view →
KIRPDFSTertileAll0.6670.864.01836view →
KIRCDFSTertileIV0.3100.642.01036view →
LUADDFSTertileAll0.8960.651.00933view →
LUSCOSTertileII,III,IV0.2560.636.01027view →
BRCAOSTertileAll0.9980.919.03124view →
CESCDFSTertileIV0.0530.529<.00118view →
LIHCDFSTertileII,III,IV0.0450.414<.00118view →
BLCADFSTertileAll0.2410.526.01918view →
THYMDFSMedianII,III,IV1.0000.560.01213view →
LGGDFSTertileAll0.3100.731.0179view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

Exploration