Across TCGA pan-cancer cohorts, TRAJ50 RNA is linked to patient survival in 7 of 34 cancer types, making it the most broadly survival-associated TRAJ50 data layer.
The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher TRAJ50 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated TRAJ50 expression acts as an unfavorable survival marker, although some lineages such as OV show a favorable association.
OV, ESCA, and STAD are the cancer types where TRAJ50 RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.