Across TCGA patient cohorts, TRAJ45 mutation is significantly associated with the RNA expression of many other genes, with 28 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRAJ45-associated genes across cancer lineages are CYP11B2, OR2AP1, and MRPL32P1. Each is linked with TRAJ45 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRAJ45-to-partner and partner-to-TRAJ45 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAJ45→partner) and Y-score (partner→TRAJ45) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CYP11B2 →	+0.078	+4.719	<.001	.003	3	1
UCEC	OR2AP1 →	+0.119	+4.852	<.001	.006	3	1
UCEC	MRPL32P1 →	+0.383	+4.694	<.001	.007	3	1
UCEC	RN7SKP220 →	+0.769	+6.245	<.001	<.001	3	1
UCEC	LINC01706 →	+0.136	+4.621	<.001	.008	3	1
UCEC	LINC02794 →	+0.130	+5.038	.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

Exploration

TRAJ45 survival (RNA) · tumor vs normal (RNA) · all TRAJ45 data types