Across TCGA pan-cancer cohorts, TRAJ41 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of TRAJ41’s most consistent transcriptional readouts.
The strongest signal is observed in stomach adenocarcinoma (STAD), where TRAJ41 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TRAJ41 is over-expressed in tumor.
STAD and KIRC are the cancer types where TRAJ41 tumor–normal differential expression is most reproducible.