Across TCGA pan-cancer cohorts, TRAJ4 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of TRAJ4’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where TRAJ4 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TRAJ4 is over-expressed in tumor.

KIRC and LUAD are the cancer types where TRAJ4 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TRAJ4 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	All	+0.460	<.001	8	view →
LUAD	All	All	+0.437	.016	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: TRAJ4 RNA expression & survival · all TRAJ4 data types