TRAJ37

Across TCGA pan-cancer cohorts, TRAJ37 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated TRAJ37 data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher TRAJ37 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated TRAJ37 expression acts as an unfavorable survival marker, although some lineages such as STAD and SKCM show a favorable association.

THCA, MESO, and STAD are the cancer types where TRAJ37 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	DFS	Tertile	II,III,IV	0.560	0.888	<.001	78	view →
MESO	OS	Tertile	III,IV	0.282	0.605	<.001	63	view →
STAD	DFS	Quartile	II,III,IV	0.715	0.296	.003	50	view →
SKCM	OS	Tertile	All	0.511	0.310	.001	39	view →
GBM	OS	Tertile	All	0.005	0.416	<.001	18	view →
TGCT	DFS	Tertile	II,III,IV	0.621	0.949	.034	18	view →
LGG	DFS	Tertile	All	0.147	0.757	<.001	18	view →
PAAD	OS	Tertile	III,IV	0.558	0.924	.014	15	view →
ESCA	DFS	Median	III,IV	0.527	0.297	.007	15	view →
DLBC	DFS	Tertile	All	0.356	0.916	.018	10	view →
THYM	OS	Median	All	1.000	0.655	.005	7	view →
LUSC	OS	Tertile	II,III,IV	0.640	0.764	.038	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

TRAJ37–THCA (DFS)

Open the THCA breakdown →