TRAJ36

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TRAJ36 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRAJ36-associated genes across cancer lineages are MIR412 and MIR4476. Each is linked with TRAJ36 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRAJ36-to-partner and partner-to-TRAJ36 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR412 grouped by TRAJ36-low versus TRAJ36-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAJ36→partner) and Y-score (partner→TRAJ36) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMIR412 →+0.621+8.066<.001.00731
UCECMIR4476 →+0.736+8.066<.001.00731
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

MIR412 by TRAJ36 expression — UCEC

Box plot of MIR412 in TRAJ36-low vs TRAJ36-high samples in UCEC.

Explore this box plot interactively →

Exploration