Across TCGA pan-cancer cohorts, TRAJ19 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of TRAJ19’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where TRAJ19 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TRAJ19 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

BRCA, KIRC, and THCA are the cancer types where TRAJ19 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TRAJ19 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	All	+0.279	.003	4	view →
KIRC	Male	All	+0.228	<.001	4	view →
THCA	Female	All	−0.226	.011	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: TRAJ19 RNA expression & survival · all TRAJ19 data types