Across TCGA patient cohorts, TRAJ18 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible TRAJ18-associated genes across cancer lineages are MIR6737, MIR7158, and USP17L4. Each is linked with TRAJ18 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRAJ18-to-partner and partner-to-TRAJ18 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAJ18→partner) and Y-score (partner→TRAJ18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MIR6737 →	+0.741	+5.867	<.001	.003	3	1
SKCM	MIR7158 →	+0.630	+7.810	<.001	<.001	3	1
SKCM	USP17L4 →	+0.039	+7.810	<.001	<.001	3	1
SKCM	RBM17P3 →	+0.052	+6.469	<.001	.001	3	1
SKCM	OR7E18P →	+0.098	+5.513	<.001	.004	3	1
SKCM	SMIM11P1 →	+0.283	+4.979	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

Exploration

TRAJ18 survival (RNA) · tumor vs normal (RNA) · all TRAJ18 data types