Across TCGA pan-cancer cohorts, TRAJ10 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of TRAJ10’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where TRAJ10 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TRAJ10 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

KIRC, BRCA, and THCA are the cancer types where TRAJ10 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TRAJ10 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	+0.287	<.001	9	view →
BRCA	Female	All	+0.268	.014	3	view →
THCA	All	All	−0.261	.017	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: TRAJ10 RNA expression & survival · all TRAJ10 data types