Across TCGA patient cohorts, TRAJ1 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRAJ1-associated genes across cancer lineages are MIR6859-2, FAM25C, and MIR6859-4. Each is linked with TRAJ1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRAJ1-to-partner and partner-to-TRAJ1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAJ1→partner) and Y-score (partner→TRAJ1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR6859-2 →	+0.745	+4.690	<.001	.003	3	1
UCEC	FAM25C →	+0.184	+5.123	<.001	.004	3	1
UCEC	MIR6859-4 →	+1.020	+4.448	<.001	.006	3	1
UCEC	MIR3146 →	+0.737	+4.499	.001	.005	3	1
UCEC	VN1R91P →	+0.486	+4.621	<.001	.008	3	1
UCEC	PCNPP2 →	+0.102	+5.226	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

Exploration

TRAJ1 survival (RNA) · tumor vs normal (RNA) · all TRAJ1 data types