TRAFD1

Across TCGA cell cohorts, TRAFD1 protein abundance is significantly associated with the RNA expression of many other genes, with 4,352 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TRAFD1-associated genes across cancer lineages are HP1BP3, GPBP1L1, and FBXO42. Each is linked with TRAFD1 in more than 8 cancer types. Because this analysis shows association rather than direction, both TRAFD1-to-partner and partner-to-TRAFD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRAFD1 versus HP1BP3 in BLOOD_Leukemia, with a Pearson correlation of 0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAFD1→partner) and Y-score (partner→TRAFD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	HP1BP3 →	+0.920	+0.856	.001	<.001	3	9
LUNG_SCLC	GPBP1L1 →	+0.833	+1.524	.003	<.001	3	7
LUNG_SCLC	FBXO42 →	+0.743	+1.581	<.001	<.001	3	7
LUNG_SCLC	ZNF436 →	+0.836	+0.986	.009	.002	3	6
PANCREAS	ZSCAN30 →	+1.154	+0.915	.001	.006	3	6
LIVER	CREBRF →	+0.578	+0.691	.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,352 associations by consensus.

TRAFD1 vs HP1BP3 — BLOOD_Leukemia

Explore this scatter interactively →