TRAF6

Across TCGA patient cohorts, TRAF6 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,915 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible TRAF6-associated proteins across cancer lineages are RPL26, RPL7A, and GRPEL1. Each is linked with TRAF6 in more than 4 cancer types. Because this analysis shows association rather than direction, both TRAF6-to-partner and partner-to-TRAF6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRAF6 versus RPL26 in LUAD, with a Pearson correlation of -0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAF6→partner) and Y-score (partner→TRAF6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RPL26 →	-0.651	-0.384	<.001	<.001	3	5
LUAD	RPL7A →	-0.311	-0.351	<.001	<.001	3	5
BRCA	GRPEL1 →	-0.457	-0.459	<.001	<.001	3	5
LSCC	MANF →	-0.553	-0.415	<.001	<.001	3	5
OV	PPP1R12C →	+0.264	+0.590	.001	.003	3	5
OV	MRPS5 →	-0.421	-0.639	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,915 associations by consensus.

TRAF6 vs RPL26 — LUAD

Explore this scatter interactively →