TRAF4

Across TCGA patient cohorts, TRAF4 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,572 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TRAF4-associated proteins across cancer lineages are SUPT6H, ZMYM3_S464, and PRPF8. Each is linked with TRAF4 in more than 6 cancer types. Because this analysis shows association rather than direction, both TRAF4-to-partner and partner-to-TRAF4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRAF4 versus SUPT6H in GBM, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAF4→partner) and Y-score (partner→TRAF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SUPT6H →	+0.259	+0.833	<.001	<.001	3	7
GBM	ZMYM3_S464 →	+0.432	+0.820	<.001	<.001	3	6
GBM	PRPF8 →	+0.265	+0.806	<.001	<.001	3	6
GBM	SF3B3 →	+0.253	+0.776	<.001	<.001	3	6
LSCC	DHX15 →	+0.240	+0.664	<.001	<.001	3	6
LSCC	LIG3 →	+0.355	+0.493	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,572 associations by consensus.

TRAF4 vs SUPT6H — GBM

Explore this scatter interactively →