TRAF4

Across TCGA patient cohorts, TRAF4 protein abundance is significantly associated with the RNA expression of many other genes, with 9,919 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TRAF4-associated genes across cancer lineages are CCN4, COLEC12, and VCAM1. Each is linked with TRAF4 in more than 5 cancer types. Because this analysis shows association rather than direction, both TRAF4-to-partner and partner-to-TRAF4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRAF4 versus CCN4 in CCRCC, with a Pearson correlation of -0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAF4→partner) and Y-score (partner→TRAF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	CCN4 →	-1.133	-0.335	<.001	<.001	3	5
GBM	COLEC12 →	-1.120	-0.534	<.001	<.001	3	5
OV	VCAM1 →	-1.500	-0.321	.001	.006	3	5
CCRCC	COL6A3 →	-1.511	-0.444	<.001	<.001	3	5
UCEC	FBLN2 →	-1.541	-0.397	<.001	<.001	3	5
OV	MSC →	-1.176	-0.397	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,919 associations by consensus.

TRAF4 vs CCN4 — CCRCC

Explore this scatter interactively →