TRAF4

Across TCGA cell cohorts, TRAF4 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,857 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible TRAF4-associated GO terms across cancer lineages are Negative regulation of mRNA catabolic process, Oocyte growth, and Negative regulation of chromosome condensation. Each is linked with TRAF4 in more than 12 cancer types. Because this analysis shows association rather than direction, both TRAF4-to-partner and partner-to-TRAF4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of mRNA catabolic process grouped by TRAF4-low versus TRAF4-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAF4→partner) and Y-score (partner→TRAF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Negative regulation of mRNA catabolic process →	+0.087	+1.195	<.001	<.001	3	13
LUNG_SCLC	Oocyte growth →	+0.176	+0.602	<.001	.007	3	13
UPPER_AERODIGESTIVE_TRACT	Negative regulation of chromosome condensation →	+0.145	+0.855	<.001	.002	3	13
UPPER_AERODIGESTIVE_TRACT	mRNA transcription →	+0.073	+0.898	.003	.005	2	13
LUNG_NSCLC_LUSC	Establishment of epithelial cell apical/basal polarity →	-0.241	-0.829	<.001	.001	3	12
LIVER	Negative regulation of RNA catabolic process →	+0.062	+1.158	<.001	.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,857 associations by consensus.

Negative regulation of mRNA catabolic process by TRAF4 expression — LIVER

Explore this box plot interactively →