Across TCGA pan-cancer cohorts, TRAF3IP1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated TRAF3IP1 data layer compared with 21 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher TRAF3IP1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated TRAF3IP1 expression acts as an unfavorable survival marker, although some lineages such as PDAC show a favorable association.

PDAC, CCRCC, and LSCC are the cancer types where TRAF3IP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Median	All	0.851	0.630	.016	14	view →
CCRCC	DFS	Quartile	All	0.579	0.833	.011	9	view →
LSCC	DFS	Quartile	II,III,IV	0.794	1.000	.005	9	view →
HNSC	DFS	Quartile	IV	0.482	0.892	.001	8	view →
LUAD	DFS	Median	All	0.656	0.956	.008	5	view →
GBM	OS	Median	All	0.748	0.876	.015	4	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

Exploration

Same gene, other analysis: TRAF3IP1 tumor-vs-normal RNA expression · all TRAF3IP1 data types