TRAF3IP1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TRAF3IP1 mutation is significantly associated with the RNA expression of many other genes, with 2,222 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRAF3IP1-associated genes across cancer lineages are RNU6-1213P, EXOGP1, and RDM1P2. Each is linked with TRAF3IP1 in more than 2 cancer types. Because this analysis shows association rather than direction, both TRAF3IP1-to-partner and partner-to-TRAF3IP1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAF3IP1→partner) and Y-score (partner→TRAF3IP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNU6-1213P →+0.155+3.069<.001.00533
LUADEXOGP1 →+0.028+5.315<.001.00332
LUADRDM1P2 →+0.205+4.194<.001.00932
LUADNXF2 →+0.011+4.984.003.00532
SKCMRNU6-1113P →+0.187+4.328<.001<.00132
HNSCRPL31P20 →+0.230+5.368<.001.00532
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,222 associations by consensus.

Exploration