TRAF3

Across TCGA patient cohorts, TRAF3 protein abundance is significantly associated with the RNA expression of many other genes, with 11,239 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TRAF3-associated genes across cancer lineages are MAP3K9, STXBP1, and CINP. Each is linked with TRAF3 in more than 3 cancer types. Because this analysis shows association rather than direction, both TRAF3-to-partner and partner-to-TRAF3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRAF3 versus MAP3K9 in GBM, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAF3→partner) and Y-score (partner→TRAF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MAP3K9 →	+0.878	+0.349	.001	<.001	3	3
UCEC	STXBP1 →	+0.644	+0.269	.006	.001	3	3
BRCA	CINP →	+0.455	+0.380	<.001	<.001	3	3
BRCA	SETD3 →	+0.310	+0.301	.004	<.001	3	3
BRCA	IFITM2 →	+0.970	+0.281	<.001	<.001	3	3
BRCA	CDC42BPB →	+0.695	+0.308	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,239 associations by consensus.

TRAF3 vs MAP3K9 — GBM

Explore this scatter interactively →