TRAF3

Across TCGA cell cohorts, TRAF3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,161 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TRAF3-associated GO terms across cancer lineages are RNA localization, Microtubule polymerization, and Establishment of RNA localization. Each is linked with TRAF3 in more than 15 cancer types. Because this analysis shows association rather than direction, both TRAF3-to-partner and partner-to-TRAF3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA localization grouped by TRAF3-low versus TRAF3-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAF3→partner) and Y-score (partner→TRAF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	RNA localization →	+0.091	+0.919	<.001	<.001	3	16
LIVER	Microtubule polymerization →	+0.117	+0.891	.005	.004	3	15
BONE	Establishment of RNA localization →	+0.099	+0.918	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Protein depolymerization →	+0.138	+1.171	<.001	<.001	3	14
KIDNEY	Response to oscillatory fluid shear stress →	+0.176	+0.844	<.001	.004	3	14
KIDNEY	Cellular response to oscillatory fluid shear stress →	+0.176	+0.844	<.001	.004	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,161 associations by consensus.

RNA localization by TRAF3 expression — BONE

Explore this box plot interactively →