TRAF1

Across TCGA patient cohorts, TRAF1 protein abundance is significantly associated with the RNA expression of many other genes, with 19,880 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TRAF1-associated genes across cancer lineages are IL21R, RASAL3, and ARHGAP9. Each is linked with TRAF1 in more than 9 cancer types. Because this analysis shows association rather than direction, both TRAF1-to-partner and partner-to-TRAF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRAF1 versus IL21R in GBM, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAF1→partner) and Y-score (partner→TRAF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	IL21R →	+1.317	+0.700	<.001	<.001	3	10
LSCC	RASAL3 →	+1.027	+0.616	<.001	<.001	3	10
OV	ARHGAP9 →	+0.924	+1.465	<.001	<.001	3	10
COAD	CCR7 →	+1.303	+0.558	.002	.008	3	10
BRCA	CD7 →	+1.249	+0.630	<.001	<.001	3	10
LSCC	CCR4 →	+1.277	+0.617	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,880 associations by consensus.

TRAF1 vs IL21R — GBM

Explore this scatter interactively →