TRAF1

Across TCGA patient cohorts, TRAF1 protein abundance is significantly associated with the protein abundance of many other proteins, with 28,408 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TRAF1-associated proteins across cancer lineages are COTL1, DOCK2, and HCLS1. Each is linked with TRAF1 in more than 9 cancer types. Because this analysis shows association rather than direction, both TRAF1-to-partner and partner-to-TRAF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRAF1 versus COTL1 in LSCC, with a Pearson correlation of 0.77.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAF1→partner) and Y-score (partner→TRAF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	COTL1 →	+0.621	+0.609	<.001	<.001	3	10
COAD	DOCK2 →	+0.897	+0.817	<.001	.001	3	10
CCRCC	HCLS1 →	+0.610	+0.708	<.001	<.001	3	10
BRCA	ITGAL →	+0.811	+0.580	<.001	<.001	3	10
OV	APOL3 →	+0.841	+1.561	.001	.001	3	10
GBM	MYO1G →	+0.703	+0.637	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 28,408 associations by consensus.

TRAF1 vs COTL1 — LSCC

Explore this scatter interactively →