TRABD

Across TCGA patient cohorts, TRABD mutation is significantly associated with the total protein of many other genes, with 35 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRABD-associated genes across cancer lineages are Caspase-7-cleavedD198, DJ-1, and EGFR_pY1068. Each is linked with TRABD in more than 1 cancer types. Because this analysis shows association rather than direction, both TRABD-to-partner and partner-to-TRABD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by TRABD-low versus TRABD-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRABD→partner) and Y-score (partner→TRABD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Caspase-7-cleavedD198 →	+1.422	+2.815	.001	.036	3	2
COAD	DJ-1 →	+0.279	+2.815	.006	.036	3	2
UCEC	EGFR_pY1068 →	-0.329	-3.700	<.001	.001	3	2
UCEC	ERK2 →	+0.244	+3.459	.001	.005	3	2
UCEC	Src_pY416 →	-0.207	-2.459	.028	.019	3	2
COAD	G6PD →	+0.335	+2.815	.001	.036	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 35 associations by consensus.

Caspase-7-cleavedD198 by TRABD expression — COAD

Explore this box plot interactively →