TRA2A

Across TCGA patient cohorts, TRA2A protein abundance is significantly associated with the RNA expression of many other genes, with 10,372 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TRA2A-associated genes across cancer lineages are PHF14, NR2C1, and CDK5RAP1. Each is linked with TRA2A in more than 4 cancer types. Because this analysis shows association rather than direction, both TRA2A-to-partner and partner-to-TRA2A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRA2A versus PHF14 in GBM, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRA2A→partner) and Y-score (partner→TRA2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PHF14 →	+0.464	+0.249	<.001	<.001	3	5
GBM	NR2C1 →	+0.403	+0.387	<.001	<.001	3	5
GBM	CDK5RAP1 →	+0.410	+0.346	<.001	<.001	3	5
COAD	PLAGL2 →	+0.893	+0.255	.002	<.001	3	5
LSCC	DDX56 →	+0.355	+0.289	.002	<.001	3	5
COAD	ANAPC1 →	+0.502	+0.267	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,372 associations by consensus.

TRA2A vs PHF14 — GBM

Explore this scatter interactively →