Across TCGA pan-cancer cohorts, TPTE2P6 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of TPTE2P6’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where TPTE2P6 RNA is repressed in tumor relative to normal tissue. In most cancer types TPTE2P6 is over-expressed in tumor, although a few such as KICH and BRCA show the opposite, repressed pattern.

KICH and BRCA are the cancer types where TPTE2P6 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TPTE2P6 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	All	II,III,IV	−0.028	.012	3	view →
BRCA	All	All	−0.021	.041	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: TPTE2P6 RNA expression & survival · all TPTE2P6 data types