Across TCGA patient cohorts, TPTE2P3 mutation is significantly associated with the RNA expression of many other genes, with 465 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TPTE2P3-associated genes across cancer lineages are PPP1R2P2, RPL26P3, and LINC02503. Each is linked with TPTE2P3 in more than 1 cancer types. Because this analysis shows association rather than direction, both TPTE2P3-to-partner and partner-to-TPTE2P3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TPTE2P3→partner) and Y-score (partner→TPTE2P3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	PPP1R2P2 →	+0.178	+3.875	.004	.008	3	1
SKCM	RPL26P3 →	+0.089	+3.661	.005	.009	3	1
SKCM	LINC02503 →	+0.033	+4.282	<.001	.009	3	1
UCEC	MIR7702 →	+0.263	+4.475	<.001	.003	3	1
UCEC	RNA5SP412 →	+1.013	+2.552	<.001	.002	3	1
LUAD	RN7SKP145 →	+0.174	+7.930	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 465 associations by consensus.

Exploration

TPTE2P3 survival (RNA) · tumor vs normal (RNA) · all TPTE2P3 data types