Across TCGA patient cohorts, TPTE2P3 mutation is significantly associated with the total protein of many other genes, with 17 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TPTE2P3-associated genes across cancer lineages are EGFR_pY1068, FoxM1, and JNK_pT183_Y185. Each is linked with TPTE2P3 in more than 1 cancer types. Because this analysis shows association rather than direction, both TPTE2P3-to-partner and partner-to-TPTE2P3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TPTE2P3→partner) and Y-score (partner→TPTE2P3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.299	-2.321	.017	.034	3	1
UCEC	FoxM1 →	+0.328	+2.321	.011	.035	3	1
UCEC	JNK_pT183_Y185 →	-0.206	-3.000	.015	.036	3	1
UCEC	MEK1 →	+0.431	+2.321	.019	.035	3	1
UCEC	mTOR_pS2448 →	-0.175	-2.302	.019	.034	3	1
UCEC	p38-MAPK_pT180_Y182 →	-0.686	-3.446	.002	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

Exploration

TPTE2P3 survival (RNA) · tumor vs normal (RNA) · all TPTE2P3 data types