TPTE2P2

Across TCGA patient cohorts, TPTE2P2 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,106 significant associations in total. STAD shows the largest number of these associations.

The most reproducible TPTE2P2-associated GO terms across cancer lineages are ERAD pathway, snRNA metabolic process, and Obsolete ubiquitin-dependent ERAD pathway. Each is linked with TPTE2P2 in more than 21 cancer types. Because this analysis shows association rather than direction, both TPTE2P2-to-partner and partner-to-TPTE2P2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ERAD pathway grouped by TPTE2P2-low versus TPTE2P2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TPTE2P2→partner) and Y-score (partner→TPTE2P2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	ERAD pathway →	+0.063	+0.076	<.001	<.001	3	22
ESCA	snRNA metabolic process →	+0.073	+0.073	<.001	<.001	3	19
ESCA	Obsolete ubiquitin-dependent ERAD pathway →	+0.080	+0.100	<.001	.001	3	19
STAD	Macromolecule methylation →	+0.061	+0.091	<.001	<.001	3	19
ESCA	Non-motile cilium assembly →	+0.064	+0.087	<.001	.001	3	19
ESCA	RNA modification →	+0.061	+0.077	<.001	.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,106 associations by consensus.

ERAD pathway by TPTE2P2 expression — STAD

Explore this box plot interactively →