TPTE2P2

Across TCGA patient cohorts, TPTE2P2 mutation is significantly associated with the total protein of many other genes, with 13 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TPTE2P2-associated genes across cancer lineages are Rab11, SF2, and Stathmin. Each is linked with TPTE2P2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TPTE2P2-to-partner and partner-to-TPTE2P2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Rab11 grouped by TPTE2P2-low versus TPTE2P2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TPTE2P2→partner) and Y-score (partner→TPTE2P2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Rab11 →	-0.175	-3.169	.028	.020	3	1
UCEC	SF2 →	-0.131	-3.156	.029	.020	3	1
UCEC	Stathmin →	+0.210	+2.833	.005	.034	3	1
UCEC	XBP1 →	-0.239	-3.000	.002	.036	3	1
UCEC	ATM →	-0.688	-3.169	.005	.020	3	1
UCEC	CD49b →	-0.318	-3.156	.041	.020	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

Rab11 by TPTE2P2 expression — UCEC

Explore this box plot interactively →