TPTE2

Across TCGA patient cohorts, TPTE2 protein abundance is significantly associated with the RNA expression of many other genes, with 39 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TPTE2-associated genes across cancer lineages are KCNA10, TRAJ22, and RNU2-63P. Each is linked with TPTE2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TPTE2-to-partner and partner-to-TPTE2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TPTE2 versus KCNA10 in BRCA, with a Pearson correlation of 0.81.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TPTE2→partner) and Y-score (partner→TPTE2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	KCNA10 →	+0.100	+1.136	<.001	.007	3	1
BRCA	TRAJ22 →	+1.950	+1.135	<.001	.007	3	1
BRCA	RNU2-63P →	+0.956	+1.135	.002	.007	3	1
BRCA	FRGCA →	+0.830	+1.135	<.001	.007	3	1
BRCA	ST6GAL2-IT1 →	+0.449	+1.136	<.001	.007	3	1
BRCA	MTND4LP7 →	+0.570	+1.136	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 39 associations by consensus.

TPTE2 vs KCNA10 — BRCA

Explore this scatter interactively →