TPT1P3

Across TCGA pan-cancer cohorts, TPT1P3 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated TPT1P3 data layer.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher TPT1P3 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated TPT1P3 expression acts as an unfavorable survival marker, although some lineages such as SKCM and READ show a favorable association.

SKCM, READ, and MESO are the cancer types where TPT1P3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	DFS	Quartile	IV	0.810	0.079	.003	38	view →
READ	DFS	Tertile	All	0.934	0.577	.003	36	view →
MESO	DFS	Median	II,III,IV	0.692	0.208	.001	27	view →
OV	OS	Median	III,IV	0.272	0.361	.026	26	view →
ESCA	OS	Median	IV	0.698	0.222	.006	18	view →
HNSC	DFS	Tertile	III,IV	0.313	0.286	.015	15	view →
COAD	DFS	Median	All	0.826	0.742	.019	13	view →
LUSC	OS	Quartile	III,IV	0.134	0.754	<.001	12	view →
PRAD	DFS	Median	All	0.874	0.713	.015	12	view →
PAAD	OS	Median	III,IV	0.629	1.000	.022	9	view →
KICH	OS	Median	III,IV	1.000	0.635	.012	9	view →
LGG	OS	Tertile	All	0.864	0.780	.011	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

TPT1P3–SKCM (DFS)

Open the SKCM breakdown →