Across TCGA pan-cancer cohorts, TPT1P2 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of TPT1P2’s most consistent transcriptional readouts.
The strongest signal is observed in colon adenocarcinoma (COAD), where TPT1P2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TPT1P2 is over-expressed in tumor, although a few such as KIRP and READ show the opposite, repressed pattern.
COAD, KIRP, and READ are the cancer types where TPT1P2 tumor–normal differential expression is most reproducible.